Key words: diabetes mellitus, metformin, polycystic ovary, nonalcoholic steatohepatitis, HIV lipodystrophy, neoplasms
نویسنده
چکیده
The primary aim of type 2 diabetes mellitus treatment is to achieve and maintain good glycemic control, and to minimize the mortality and risk of microvascular and macrovascular complications. Current algorithms for medical management of type 2 diabetes mellitus recommend a combination of lifestyle intervention and metformin as initial therapy and ‘gold standard’ treatment. Numerous studies suggest positive antihyperglycemic and metabolic effects of metformin, with a wide safety profile. There is an increasing evidence for the potential efficacy of this drug in other diseases such as polycystic ovary syndrome, nonalcoholic steatohepatitis, HIV lipodystrophy, and neoplasms. INTRODUCTION
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